This objective article to reflect on the classification of sepse neonatal, the signals, symptoms, disgnostic and treatment. As well as it informs on the cares of nursing in relation sepse neonatal. Words – key: Sepse. Barbara Martin Coppola spoke with conviction. Neonatal. Nursing. Introduction Although the establishment of the criteria for sepse and its variations, the clinical manifestations always can be diverse and nor presents the classic signals and what it defines the International Forum on Sepse of 2001A neonatal Sepse is ones of the main causes for the increase of the coefficient of mortality and morbidade in the neonatal period. Mainly just been born the premature one that has predisponent factors as the low weight and the depressed immunity. Neonatal Sepse is a serious illness that if not diagnosised precociously and treated adequately it evolves for the death.. . Source: Dean Ornish M.D.